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父亲给儿子吃大雕,感受那份难以抹去的情感与回忆》
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父亲给儿子吃大雕,感受那份难以抹去的情感与回忆》

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西藏自治区

  一、重大违法强制退市

  4月18日,深交所发布《关于海南普利制药股份有限公司股票及可转换公司债券终止上市的公告》。根据公告,深交所对*ST普利(维权)股票及可转债作出终止上市决定。同日,*ST普利发布相关公告称,公司股票及可转债将于2025年4月28日起进入退市整理期交易,退市整理期为十五个交易日,预计最后交易日期为2025年5月21日。

  至此又一上市公司“陨落”。上海沪紫律师事务所刘鹏律师提示退市之外,公司仍需面临虚假陈述引发的投资者索赔事宜,3月21日,公司收到证监会的处罚决定。公司暴雷之后已有不少投资者主动参与维权,部分案件即将开庭。

  投资者于2022年4月26日-2024年4月16日期间买入,并在2024年4月17日之后卖出或仍持有而亏损的即可报名索赔。

  二、财报造假被严惩

  据公告,证监会认定公司通过虚构成品药和原料药销售业务、开展贸易业务按总额法核算的方式,虚增收入和利润。经计算,公司2021年、2022年虚假记载的营业收入金额合计达10.31亿元,且占该两年披露的年度营业收入合计金额的31.08%;虚假记载的利润总额金额合计达6.95亿元,且占该两年披露的年度利润总额合计金额的76.72%。证监会决定对公司责令改正,给予警告并处以1000万元罚款,相关责任人纷纷领罚。

  刘鹏律师提示该公司审计机构或难逃此咎,作为上市公司财务报表的“把关人”,会计所出具的每一份审计意见都影响着投资者对上市公司财务状况、经营情况的判断。该公司审计机构已被中国证监会调查,如被认定为违规主体,在对该公司的维权诉讼可将该审计机构一同列为被告。

  (本文由上海沪紫律师事务所刘鹏律师供稿,不代表新浪财经的观点。刘鹏律师,专注证券维权19年,自2006年执业以来,成功为中青宝、国华网安(维权)、劲嘉股份(维权)等300余家上市公司的中小投资者成功维权,案件在办数量超过14000起,胜诉率达99.2%。作为业内资深证券维权律师,刘鹏律师精准把握案件核心,诉讼经验丰富,索赔策略高效,为投资者争取最大权益,维权实力行业领先。证券维权,选对律师是关键!专业决定胜算,经验确保结果,首选刘鹏律师,让您的索赔更稳妥、更高效!)

  作为国内疫苗行业的标杆企业,智飞生物2024年交出了一份令市场震惊的成绩单:全年营业收入260.7亿元,同比腰斩(-50.74%);归母净利润20.18亿元,降幅达74.99%。更值得警惕的是,经营性现金流首次转负至-44.14亿元,资产负债率攀升至62.3%,创下近五年新高。这种营收、利润、现金流“三杀”的局面,暴露出公司深层次的发展危机。

  核心代理业务断崖式下跌是业绩滑坡的直接推手。默沙东HPV疫苗批签发量呈现灾难性下滑:四价疫苗全年仅46.6万支,同比暴跌95.5%;九价疫苗3114万支,降幅14.8%。这两款曾贡献超90%营收的“现金牛”产品退潮,直接导致代理业务收入从2023年的695亿元骤降至2024年的239亿元。更严峻的是,自2024年三季度起连续三个季度净亏损,2025年一季度亏损扩大至3.05亿元,显示颓势仍在延续。

  自主产品难当大任的结构性矛盾显露无遗。尽管自主疫苗收入增长14.98%至11.82亿元,但占总营收比重仅4.53%。高毛利率(80%+)的EC诊断试剂、AC-Hib联合疫苗等产品,在规模化生产能力和市场渗透率上仍显不足。代理业务24.98%的毛利率与自主产品的悬殊差距,折射出公司盈利能力对单一代理产品的深度依赖。

  为何遭遇营收、利润、现金流“三杀”?

  行业周期性调整叠加需求透支构成外部冲击。后疫情时代疫苗消费呈现“K型分化”:新冠相关产品需求断崖式下跌,常规疫苗受经济下行与接种意识波动影响。中国疫苗行业协会数据显示,2024年二类苗总体批签发量下降37%,其中HPV疫苗市场缩水42%。这种系统性调整使得高度依赖代理模式的智飞生物首当其冲。

  战略失衡埋下隐患。过度依赖默沙东的“寄生式增长”模式风险集中爆发:代理产品营收占比长期维持在90%以上,但合作协议将于2026年到期,续约主动权完全掌握在外方手中。这种模式在行业上行期能快速做大规模,但缺乏技术护城河的弊端在市场转折时暴露无遗。研发投入的滞后性更令人担忧:2024年研发费用12.3亿元,占营收比4.7%,远低于国际疫苗巨头15%-20%的行业标准。

  市场竞争格局剧变加速危机。默沙东在男性HPV疫苗市场的布局虽具前瞻性,但GSK、万泰生物等竞品已形成合围之势。GSK的带状疱疹疫苗2024年批签发量达377.6万支,万泰生物的二价HPV疫苗通过WHO预认证打开出海空间。而智飞生物自主管线中,23价肺炎疫苗、四价流感疫苗等产品仍处研发后期,短期内难成气候。

  如何破局?

  战略重心向自主创新倾斜成为必然选择。控股宸安生物进军GLP-1赛道展现战略转向,司美格鲁肽注射液三期临床如能顺利推进,有望在千亿级减肥药市场分羹。但需警惕生物类似药研发的高风险性,2023年全球糖尿病药物研发失败率达62%的行业数据提示需建立风险对冲机制。建议采用“自主研发+licensein”双轮驱动,如在mRNA技术平台、多联多价疫苗等前沿领域加强布局。

  渠道价值重估与生态重构迫在眉睫。覆盖3万个基层网点的渠道网络是核心资产,但当前主要服务于代理产品配送。应转型为开放式疫苗服务平台:一方面深度绑定默沙东、GSK等国际药企,争取新型带状疱疹疫苗、呼吸道合胞病毒疫苗等产品的区域代理;另一方面打造智慧接种管理系统,通过数字化工具提升终端服务能力,挖掘成人疫苗市场的长尾需求。

  男性健康市场开拓存在战略机遇。默沙东HPV疫苗男性适应证获批创造了增量空间,但需破解认知度低的难题。可借鉴GSK在美国的营销经验,与体检机构、保险公司合作开发“健康管理套餐”,将HPV疫苗接种与男性健康筛查捆绑推广。据沙利文预测,中国男性HPV疫苗市场潜在规模超200亿元,若能抢占30%份额,可贡献60亿增量收入。

  站在行业变革的十字路口,智飞生物正经历从“渠道商”向“创新者”的艰难转身。短期阵痛难以避免,但疫苗行业长坡厚雪的特性未改——随着人口老龄化催生带状疱疹疫苗需求、消费升级激活成人疫苗市场、技术创新打开治疗性疫苗空间,具备全产业链布局能力的企业终将穿越周期。对于投资者而言,此刻更需要关注的是研发管线推进速度、战略合作深化程度以及现金流改善迹象,这些要素将决定这家疫苗龙头能否在行业洗牌中重获新生。

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