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深圳市(福田区、龙岗区、宝安区、盐田区、罗湖区、坪山区、南山区、光明区、龙华区)

  Deepseek的爆火,各行各业也相继迎来了属于自己的“AI时刻”。华安基金是业内最早深耕科技投资的基金公司之一,在数字经济与硬科技双轮驱动的时代,华安基金已构建起全面覆盖产业链、融合量化与基本面研究的立体化科技投资体系。

  这支集结产业学术背景+投研实力的“华安基金科技联盟”中,就有一位深耕在创新药”和“AI医疗”领域的基金经理——桑翔宇,他认为医药产业发展源于需求侧的“三医联动”改革,并受益于中国医药产业创新结构的巨大升级,国产创新药已经从1.0的仿创时代进入2.0的原创创新弯道超车时代。

  中国在软件生态应用端的开发变现能力远强于欧美,医药行业作为数据最具颗粒度、需求前景最广阔的垂类领域,结合AI的应用拓展未来潜力巨大。2025年医药行业即将迎来确定性的向上复苏拐点,因此桑翔宇将今年的投资重点聚焦到了创新药+AI医疗投资方向上。

  寻找两大共振:产业周期+个股周期

  桑翔宇拥有生物工程+经济学复合背景,8年研究员和1年半投资经理履历,完整经历过医药牛熊周期,善于抓行业的景气趋势机会、偏好左侧布局产业技术爆发拐点、力求挖掘有认知差的黑马股;同时,高仓位和相对集中持股的运行风格,也让桑翔宇更注重风险控制,通过高颗粒度的跟踪、灵活调整组合、交易上设置止损线和部分止盈规则,来给到投资人更稳定的长期体验。

  具体来看投资框架,桑翔宇专注寻找产业周期和个股周期的共振,在中国医药发展的确定性趋势中寻找认知差、做乘势而上企业的收集者。

  在桑翔宇看来,首先,医药是政策影响权重极大的行业,理解政策定调有利于指导组合的风险偏好并抓住结构性的风险和机遇;其次,医药产业伴随城镇化、国际化曾诞生医疗服务、CXO等长牛板块,理解产业周期决定了投资思路;最后,对创新时代产品迭代趋势和技术升级特点的理解是挖掘超额收益的核心,技术周期脉络指明了投资方向。

  对于个股挖掘,桑翔宇觉得这是一个把书读厚、再读薄的过程,他通过中观的跟踪框架、个股财报和产业跟踪等维度,在变化中理解公司,同时将研发进化能力以及企业家品质设定为所有模型假设兑现的核心。

  在获取超额收益上,桑翔宇非常重视困境反转和0-1.x阶段的公司。困境反转的公司往往存在巨大预期差,进入0-1阶段,公司此时更容易获取β的收益;1-2则是不同禀赋公司跑出差距的阶段,也是寻找β和α共振的重要窗口期;当进入2-10阶段,则需要基金经理在判断正确景气趋势前提下,不断加强仓位、获得超额收益。

  2025迎来医药复苏拐点之年

  过往持续4年医药行业的低迷,本质是一系列收缩性政策导致医药部分子行业的成长性断崖式下降,以及不确定性带来的风险偏好急速降低。

  随着国内一系列具备实操性解决集采痛点的优化文件浮出水面,商保作为基本医疗保险的重要补充在今年也会迎来重大的实质性推进,这对于解决收支压力以及创新药量价体系的提升是极大利好。

  桑翔宇格外聚焦“创新”二字,他认为今年中国创新药产业迎来了三端共振,首先是政策端医保局给予了创新药最大的支持,首发定价松绑、现金回款改善;其次,供给端中国在ADC、双抗等领域逐步实现了对于欧美的弯道超车,海外MNC蜂拥而至抢购中国资产;最后,报表端多数龙头企业迎来盈亏平衡拐点,高收入增速未来会确定性带动利润端加速提升。

  此外,国内医院层面高质量、大规模、多维度的医疗数据也是值得深度挖掘的数据金矿,在此基础上孵化的AI应用会成为医药投资变革重要推动力。

  医药投资两大解法:创新药+AI医疗

  对于未来的行业发展和医药投资,桑翔宇看好创新药和AI医疗两大解法。

  第一,创新药仍处于产业加速向上的周期,今年也有强基本面的兑现支撑。在既往ADC、PD1/VEGF等技术爆发之后,TCE、ProTac等新技术已经看到萌芽开花;同时,创新药从可预期的BD潮走向盈利潮,以往大家对创新药的疑虑是研究壁垒高、企业没盈利,因此不敢投,但随着未来企业的收入高增速带动利润的快速提升,就进入了投资者可理解的范畴内。

  第二,AI医疗有望成为2025的年度投资主题,与其它国家相比,我国AI医疗的底座能力强、具备先发优势和互联网化的运维能力。目前,国内AI医疗已发展出三种商业模式,分别为AI+制药、AI+Biotech和AI+医疗。

  其中,AI+制药主打“卖铲人”逻辑,通过AI加速新药的研发。AI+Biotech则是药企利用AI开发新靶点、新机制;AI+医疗是通过诊疗数据变现,实现降本增效和商业逻辑提升,赋能医疗的各个环节。

  展望AI医疗的发展终局,“互联网大厂+医药公司+头部医院”合作的商业化模式具备竞争优势,在B端利用高质量数据训练出高质量模型,再进一步向C端辐射,可能是未来产业发展演化路径。桑翔宇将重点关注有数据的企业,尤其是与大厂合作、与高能级医院有科室共建、能获取优质数据的企业。

  风险提示:基金管理公司不保证本基金一定盈利,也不保证最低收益。基金的过往业绩并不预示其未来表现,基金管理人管理的其他基金的业绩并不构成基金业绩表现的保证。我国基金运作时间较短,不能反映股市发展的所有阶段。基金有风险,投资需谨慎,详情请认真阅读本基金的基金合同、招募说明书等基金法律文件。

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